Final answer:
The Noche en Mexico is the Pluckers cocktail made with two ingredients, tequila and lime juice, and a spicy ranch salt rim.
Step-by-step explanation:
The cocktail from Pluckers that is made with only two ingredients and comes with a spicy ranch salt rim is the Noche en Mexico. This drink is designed to be simple yet flavorful, combining tequila and freshly squeezed lime juice, edged with a distinctive spicy ranch salt for a unique taste experience. It is not as complex as other cocktails like the Moscow Mule, Margarita, or Long Island Iced Tea, which typically involve more ingredients.