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Which of the following are examples of chemokines?

A) IL-8
B) CXCL-1
C) CXCL-2
D) TNF-α

1 Answer

6 votes

Final answer:

Chemokines include IL-8, CXCL-1, and CXCL-2, which are cytokines involved in chemotaxis. TNF-α is a cytokine but not a chemokine.

Step-by-step explanation:

Examples of chemokines include IL-8, CXCL-1, and CXCL-2. These chemotactic cytokines play a crucial role in recruiting specific subsets of leukocytes to infections, damaged tissue, and sites of inflammation. They are produced by a variety of cells and are key players in the body's early induced responses as well as during adaptive immune responses.

However, TNF-α (Tumor Necrosis Factor-alpha) is not a chemokine; it is a distinct cytokine known for its role in inflammation and immune system regulation, which can have phagocytic activity and produce chemicals promoting inflammation.

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