Final answer:
The Epic of Gilgamesh, written around 2100 BCE, is set in ancient Mesopotamia near the Tigris and Euphrates rivers and tells the story of King Gilgamesh of Uruk.
Step-by-step explanation:
The Epic of Gilgamesh is one of the oldest known pieces of literature in the world and hails from ancient Mesopotamia. It was written down in its current form around 2100 BCE. This epic tale unfolds in the historical region near the Tigris and Euphrates rivers, within an area that witnessed the early development of cities and writing. The narrative centers on the semi-divine King Gilgamesh of Uruk, and his various adventures alongside his companion Enkidu, delving into themes of power, leadership, friendship, the human condition, and the quest for immortality in the face of inevitable death.