Final answer:
Sir Isaac Newton did not have a wife nor children. He was a significant figure in the scientific revolution, contributing profound insights into physics and mathematics, without marrying or having family concerns to manage.
Step-by-step explanation:
Sir Isaac Newton, who was born in 1642 and died in 1727, was a foundational figure in the history of science, known for his groundbreaking work in physics and mathematics. However, when it comes to Newton's personal life, it is notable that he never married. Consequently, Sir Isaac Newton did not have a wife nor children. The question might stem from confusion with other historical figures who had notable marriages and offspring. During his lifetime, Newton made significant contributions to the field of natural philosophy, which is now known as science, by developing the laws of motion and gravitational theory. His influential work, Philosophiae Naturalis Principia Mathematica, often referred to as the Principia, marked a revolutionary step forward in the understanding of the physical universe.