Final answer:
Victoria Nuland is the female lead in the State Department tour of P and B, serving as the Under Secretary of State for Political Affairs.
Step-by-step explanation:
The female lead in the State Department tour of P and B was Wendy Sherman. She served as the Under Secretary of State for Political Affairs from 2011 to 2015. Sherman played a key role in negotiating the Iran nuclear deal during the Obama administration.
The female lead in the State Department tour of P and B referred to in the question is Victoria Nuland, who as of the current knowledge cutoff date, serves as the Under Secretary of State for Political Affairs, making her a key official in the State Department.
Her efforts in diplomacy and international relations often place her in a leading role in various tours and missions, including negotiations and policy discussions. It's vital to note that specific details of tours can change, but based on the positions held by the individuals listed in the options, Victoria Nuland stands out as having a leading role in political affairs within the State Department.