Final answer:
Bed bugs are nocturnal and most active from midnight to dawn, aligning with their feeding habits on sleeping humans.
Step-by-step explanation:
Bed bugs are insects that exhibit nocturnal behavior, meaning they are most active at night. In the case of bed bugs, this period of activity coincides with the time when people are typically asleep, which is from midnight to dawn. It aligns with their feeding habits as they feed on the blood of humans, often without being detected. Much like other nocturnal creatures such as bats and owls, bed bugs use the cover of darkness to carry out their activities, maximizing their chances of feeding without interruption. Hence, the correct answer to the question "Bed bugs are most active during" is option B, Midnight to dawn.