Final answer:
Oil-soluble formulations offer the greatest possibility of dermal absorption.
Step-by-step explanation:
Among the given options, oil-soluble formulations offer the greatest possibility of dermal (skin) absorption. Oil-soluble formulations, such as creams, lotions, and ointments, are able to penetrate the skin more effectively due to their lipid-based nature.
Oil-in-water (O/W) creams, which are composed of small droplets of oil dispersed in a continuous water phase, are commonly used as they provide better cosmetic acceptability and are easily washed off with water. Water-in-oil (W/O) creams, on the other hand, are more moisturizing and provide an oily barrier that reduces water loss from the skin.