Final answer:
All of the statements about acute hepatitis E in the United States are true: it is usually acquired through travel to high-endemic areas, can be serious and lead to liver failure, and there is no vaccine available for it in the United States.
Step-by-step explanation:
Regarding the question: Virtually all cases of acute hepatitis E seen in the United States occur among travelers returning from high endemic areas. Which of the following statements is true about acute hepatitis E in the United States? The correct answer is D. All of the above.
Acute hepatitis E is indeed most commonly acquired through travel to high-endemic areas. The virus is typically spread by the fecal-oral route through consumption of contaminated food and water. As such, travelers to regions where hepatitis E is common are at risk of contracting the virus.
It can also be a serious illness, which in rare cases, may lead to liver failure, particularly in vulnerable groups such as pregnant women. Furthermore, while vaccines for hepatitis A and B are readily available and recommended, there is currently no vaccine available to prevent hepatitis E that is approved for use in the United States.