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Acyclovir and coronavirus Studies indicated that adenosine analogues revealed high efficacy as RNA polymerase inhibitors. What service does Creative Biolabs offer concerning adenosine analogues?

a) Clinical trials for COVID-19 treatment
b) Development and synthesis of adenosine analogues
c) Customizing RNA polymerase inhibitors
d) Characterization of coronavirus strains

User Hobblin
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1 Answer

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Final answer:

Acyclovir is an antiviral drug that interferes with herpes virus DNA replication by mimicking the nucleoside guanosine. Adenosine analogues, which are related in function and target RNA polymerases, are part of ongoing research to combat viruses, including coronaviruses. Creative Biolabs likely offers services including the development and synthesis of such analogues.

Step-by-step explanation:

Acyclovir is an antiviral guanosine analog specifically designed to inhibit DNA replication in herpes viruses. Its activation requires the viral enzyme thymidine kinase, which then allows it to incorporate into the viral DNA, causing chain termination. This specificity makes acyclovir highly effective against herpes virus infections. The compound behaves as a chain terminator because of its resemblance to guanosine but lacks the required elements to continue DNA polymerization. Adenosine analogues have shown high efficacy as RNA polymerase inhibitors, making them of great interest in antiviral research and treatment, particularly for RNA viruses such as coronaviruses. There is continuous effort in the research and development of these analogues due to their potential therapeutic properties, including inhibition of viral enzymes and overcoming mutations within viral genomes. Creative Biolabs may offer services such as the development and synthesis of adenosine analogues, as they are involved in identifying new antiviral agents which could include the design and synthesis of these compounds.

User Carlos Mora
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