Final answer:
The statement is true; B-Lymphocytes mature in the bone marrow while T-Lymphocytes mature in the thymus.
Step-by-step explanation:
The statement that the difference between B-Lymphocytes and T-Lymphocytes is that T-cells specialize (receive special training) in the thymus is True. Both types of cells are produced in the red bone marrow. While B-Lymphocytes, or B cells, mature in the red bone marrow itself, T-Lymphocytes, or T cells, migrate to the thymus gland to complete their maturation. The maturing process includes learning to distinguish self from non-self and ensures that each type of lymphocyte is equipped to play its distinct role in the immune response.