Final answer:
Three negative effects of exploration were disease spread, displacement of indigenous people, and exploitation of resources.
Step-by-step explanation:
Three negative effects of exploration on both Europe and the New World were disease spread, displacement of indigenous people, and exploitation of resources.
When European explorers reached the New World, they unknowingly brought diseases like smallpox and measles, which devastated the Native American populations who had no immunity.
The arrival of Europeans also led to the displacement and forced labor of indigenous people, as well as the confiscation of their land and wealth.
Additionally, the exploitation of resources by Europeans, such as the extraction of valuable minerals and the establishment of plantations, resulted in environmental degradation and loss of local control over resources.