Final answer:
Both humoral and cellular immune responses involve T lymphocytes, with humoral immunity using B cells to produce antibodies for extracellular pathogens, and cellular immunity using T cells to eliminate intracellular pathogens.
Step-by-step explanation:
One similarity between humoral and cellular responses is that both rely on the activation of T lymphocytes. While humoral immunity involves B cells producing antibodies to fight pathogens in the extracellular spaces, cellular immunity involves T cells that target and eliminate pathogens inside the host cells. T cells also help coordinate the overall adaptive immune response, which includes both humoral and cellular defense strategies.