Final answer:
Pathogens most commonly enter through breaks in the skin, with hair follicles and sweat glands being potential entry points when associated with injuries.
Step-by-step explanation:
Pathogens commonly gain entry into the body through breaks in the skin such as cuts, abrasions, or punctures. Although the skin is a formidable barrier with its layer of dry, keratinized epithelial cells and its acidic, low-moisture environment that inhibits microbial growth, pathogens can breach this first line of defense when the integrity of the skin is compromised. Hair follicles and sweat glands can also serve as entry points, particularly if they're associated with minor injuries or if pathogens are introduced into these areas through other means. Moreover, specialized cells in the skin, like Langerhans cells, help thwart infections by phagocytizing invaders. Thus, maintaining unbroken skin and promptly treating any wounds is crucial in preventing pathogen entry and subsequent infection.