Final answer:
When a heterozygous running mouse (Rr) is crossed with a homozygous circling brown mouse (rrbb), approximately 25% of the offspring will be circling running and brown.
Step-by-step explanation:
To determine the percentage of offspring that will be circling running and brown, we need to consider the inheritance of two traits: the ability to run normally and hair color. In this case, running normally (R) is a dominant trait, and running in circles (r) is recessive. Black hair (B) is dominant over brown hair (b).
When we cross a heterozygous running mouse (Rr) with a homozygous circling brown mouse (rrbb), we can use Punnett squares to visually represent the possible genotypes and phenotypes of the offspring.
The potential genotypes of the offspring will be: RrBb, Rrbb, rrBb, and rrbb. After crossing the parental genotypes, we see that 25% of the offspring will be circling running and brown (rrbb). Therefore, the percentage of the offspring that will be circling running and brown is 25%.