Final answer:
During the proliferative phase of wound-healing, fibroblasts are responsible for building new tissue that resembles the original by secreting collagen.
Step-by-step explanation:
During the proliferative phase of wound-healing, fibroblasts build a new tissue that takes the shape of the original tissue by secreting collagen. Fibroblasts mobilize and divide rapidly to repair damaged tissue through collagen deposition, forming granulation tissue that eventually heals the wound. Angiogenesis accompanies this process, promoting vascularization and increasing blood circulation to the area, which is critical for tissue repair. Immune cells, including macrophages, are also present and work to clear any foreign matter, reducing infection risks. This response is part of the body's natural healing process after containment of an injury.