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One of the two types of GTP-binding proteins, often called G-proteins, are membrane bound. These are the:

a. trimeric GTP-binding proteins.
b. monomeric GTP-binding proteins.
c. G-protein coupled receptors.
d. cyclic GMPs.

User Nfirvine
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1 Answer

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Final answer:

The correct answer is option a. The membrane-bound GTP-binding proteins are known as trimeric GTP-binding proteins or heterotrimeric G-proteins. They play a crucial role in signal transduction by interacting with G-protein-coupled receptors and regulating cellular responses.

Step-by-step explanation:

The student is asking about the type of GTP-binding proteins that are membrane-bound. These membrane-bound proteins are involved in signal transduction and interact with the cell's membrane receptors to initiate a cellular response. Two main types of GTP-binding proteins are involved in these processes: trimeric GTP-binding proteins, also known as heterotrimeric G-proteins, and monomeric GTP-binding proteins, which include small GTPases like Ras and Rho. In the context of the question, which focuses on membrane-bound GTP-binding proteins, the correct answer is trimeric GTP-binding proteins.

These proteins, also referred to as G-proteins, are vital for numerous cellular functions including signal transduction. When a signaling molecule like a hormone binds to a G-protein-coupled receptor (GPCR) in the plasma membrane, the GDP molecule associated with the alpha (α) subunit of the G-protein is exchanged for GTP, causing the beta (ß) and gamma (γ) subunits to dissociate. This exchange initiates various cellular responses. Notably, stimulatory G-proteins are designated Gs, while inhibitory G-proteins are designated Gi.

In conclusion, the type of GTP-binding proteins that are membrane-bound are the trimeric GTP-binding proteins. This is option (a) in the multiple-choice question the student has presented.

User Jeff Squyres
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