Question

Anemia that results from a lack of intrinsic factor essential for the absorption of vitamin B12 is _____ anemia.

1) Pernicious
2) Iron-deficiency
3) Sickle cell
4) Aplastic

Answer 1

Anemia resulting from a lack of intrinsic factor needed for vitamin B12 absorption is pernicious anemia. The correct option is 1.

Step-by-step explanation:

Pernicious anemia is a condition where the body is unable to properly absorb vitamin B12 due to a deficiency of intrinsic factor, which is necessary for vitamin B12 absorption in the intestine. This type of anemia is often associated with certain conditions such as Crohn's disease or following surgical removal of parts of the stomach or intestines.

Distinguishing between different types of anemia is crucial for treatment since each type has its specific cause and necessary intervention. For example, iron deficiency anemia, which is the most common type, occurs due to insufficient iron levels, while vitamin-deficient anemias are related to insufficient intake or absorption of vitamins such as B12 and folate.

Unlike pernicious anemia, sickle cell and aplastic anemias are caused by faulty or decreased red blood cell (RBC) production.

It is especially important for individuals who have had bariatric surgery or suffer from gastrointestinal disorders, for vegans and vegetarians, and in the early stages of pregnancy to monitor and maintain proper levels of vitamin B12 and folate to prevent the onset of pernicious anemia and other associated health complications. Hence, 1 is the correct option.