Final answer:
If a train operator activates a route request button due to a wrong route signal and gets no response from the tower, they must not proceed. Confirmation from the tower is critical for safety on the railways.
Step-by-step explanation:
If a train operator pulls up to a signal indicating a wrong route and operates the route request button and receives no acknowledgement from the tower operator, it would be improper for the train operator to proceed. It is essential for train operators to wait for an explicit signal change or approval from the tower before moving ahead, especially in situations where potential track conflicts could arise. Operating without tower confirmation could lead to dangerous situations and possibly accidents. The interlocking signal systems and route request buttons are vital for maintaining the safety and efficiency of railway operations.