Question

When can we give TPA in an MI?

1) During the acute phase of MI
2) After the acute phase of MI
3) Before the acute phase of MI
4) TPA is not used in the treatment of MI

Answer 1

TPA is used during the acute phase of a myocardial infarction to help break down blood clots. It is most effective when administered quickly after symptom onset. Additional treatments include oxygen, aspirin, and nitroglycerine.

Step-by-step explanation:

Tissue plasminogen activator (TPA) is used in the treatment of myocardial infarction (MI), specifically during the acute phase of MI. TPA acts as a thrombolytic agent that catalyzes the conversion of plasminogen to plasmin, thus aiding in the breakdown of blood clots. This treatment is most effective when administered as soon as possible after the onset of MI symptoms. Administering TPA after the acute phase is less beneficial and is not the standard of care. TPA is not given before the acute phase as it is intended to treat an existing thrombotic event. Immediate treatments for MI also include supplemental oxygen, aspirin, and nitroglycerine. These interventions aim to provide rapid relief and stabilization of the condition. If the damage to the heart muscle is extensive, more invasive procedures like balloon angioplasty, stent placement, bypass surgery, or even the implantation of coronary assist devices might be necessary.