Final answer:
Aspirin should not be given to individuals 18 years and younger due to the risk of Reye's Syndrome, especially during a viral infection. Ibuprofen and paracetamol are safer alternatives for pain relief and fever reduction in children when used correctly.
Step-by-step explanation:
The drug that should not be given to a person 18 years and younger is aspirin. This recommendation is due to the risk of Reye's Syndrome, a rare but serious condition that can cause brain swelling and may be fatal, particularly when aspirin is taken during a viral infection. While ibuprofen and paracetamol (also known as acetaminophen) can be used by children, it is important to follow dosage guidelines carefully. Antibiotics are prescribed based on specific infections and are not categorically unsafe for those under 18 but must be used responsibly to avoid issues such as antibiotic resistance.