Final answer:
Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organs, including the skin, joints, and kidneys, characterized by the production of autoantibodies like anti-nuclear antibodies (ANAs).
Step-by-step explanation:
Systemic Lupus Erythematosus (SLE)
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect various parts of the body. Unlike diseases that target specific organs, SLE has the potential to damage multiple organs and tissues. The correct answer to the question is (4) Multiple organs including the skin, joints, and kidneys. SLE may cause a wide range of symptoms, including psychological fatigue, butterfly rash on the face, joint arthritis, and muscle aches, due to the immune system mistakenly attacking the body's own healthy cells. The production of autoantibodies, such as anti-nuclear antibodies (ANAs), leads to nuclear and cellular destruction and is a hallmark of SLE. Common symptoms also include fever, photosensitivity, mouth and nose ulcers, involvement of the pleura and pericardium, and potential kidney damage.