Final answer:
Digoxin toxicity is likely to occur in clients with low levels of potassium or magnesium, decreased renal function, and those who have an overdose of digoxin, as these conditions enhance the effects of digoxin or hinder its excretion.
Step-by-step explanation:
When caring for a client on digoxin (Lanoxin) therapy, the practical nurse should be vigilant for signs of digoxin toxicity. The client is likely predisposed to developing digoxin toxicity if they experience conditions such as electrolyte imbalances, particularly low levels of potassium (hypokalemia) or magnesemia, decreased renal function, and an overdose of digoxin. Low potassium levels can increase the sensitivity of the heart to digoxin, thereby enhancing its effects and predisposing the individual to toxicity. Furthermore, decreased renal function can lead to an accumulation of digoxin in the body because digoxin is primarily excreted through the kidneys. Health care providers should monitor electrolyte levels, renal function, and be cautious with dosing, especially in populations at risk, such as the elderly or those with kidney disorders.