Final answer:
The ingestion of toxic chemicals can harm the renal tubules, impairing their ability to reabsorb water and essential nutrients. This can result in increased excretion of substances in the urine.
Step-by-step explanation:
The ingestion of toxic chemicals can have harmful effects on the renal tubules, which are a part of the kidneys responsible for filtering waste substances from the blood. Toxic chemicals can cause damage to the cells of the renal tubules, leading to a decrease in their ability to reabsorb water and essential nutrients. This can result in an increased excretion of substances such as amino acids, peptides, glucose, and uric acid in the urine.
For example, excessive deposition of copper in the kidneys can cause renal tubular damage and lead to increased urinary excretion of amino acids, peptides, and glucose.
It's important to note that the specific effects of toxic chemicals on the renal tubules can vary depending on the type and dose of the chemical ingested.