Final answer:
Victor's advice to Walton's crew in 'Frankenstein' is to turn back and avoid the dangers of unrestrained pursuit of knowledge, highlighting the novel's cautionary theme about unchecked ambition.
Step-by-step explanation:
In Mary Shelley's Frankenstein, Victor's advice to Walton's crew is to turn back and avoid dangerous pursuits (B). This advice is significant because it encapsulates the central theme of the novel: the consequences of unchecked ambition and the pursuit of knowledge. Victor's tragic story serves as a cautionary tale about the potential perils of pushing beyond natural boundaries in the pursuit of scientific progress. This theme resonates throughout the book, from Victor's isolated education fostering his tragic ambition to the creature's struggle with isolation and his own education.