Final answer:
The most effective use of guaifenesin (Mucinex) is to take the tablet with a full glass of water.
Step-by-step explanation:
The most effective use of guaifenesin (Mucinex) is to take the tablet with a full glass of water. Guaifenesin is an expectorant that helps to thin and loosen mucus in the airways, making it easier to cough up. Taking it with water ensures that it is properly absorbed and can effectively work to alleviate congestion and cough.