Final answer:
The nurse should notify the health care provider immediately, as blood in the urine may indicate a serious condition.
Step-by-step explanation:
When a client taking rifampin (Rifadin) reports brown urine with blood, it is important for the nurse to take action. While rifampin can cause urine discoloration, blood in the urine should not be considered a normal response to the medication. This finding could indicate a more serious condition, such as a urinary tract infection or kidney stone. The nurse should notify the health care provider immediately for further assessment and intervention.