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Which of the following chemical equations best describes the reduction of the coenzyme NAD?

A) NAD + 2H+ + 2e- → NADH
B) NADH → NAD + 2H+ + 2e-
C) 2NADH → 2NAD + H2
D) NAD + H2 → NADH

1 Answer

5 votes

Final answer:

The correct equation for the reduction of NAD is A) NAD + 2H+ + 2e- → NADH, representing the gain of electrons and protons in a redox reaction that is fundamental to cellular metabolism.

Step-by-step explanation:

The correct option : a

The process of converting the oxidized form of nicotinamide adenine dinucleotide (NAD+) to its reduced form NADH involves the addition of two protons (H+) and two electrons (e-). This reduction reaction is an example of an oxidation-reduction (redox) reaction that is crucial in biological systems, particularly in the metabolic pathways where energy in the form of ATP is generated. These reversible reactions where NAD+ is reduced to NADH and vice versa, are essential in the transfer of energy and electrons within cells during processes such as cellular respiration and photosynthesis.

The structure of NAD+ includes a nicotinamide ring that accepts a hydride ion (H-), which accounts for the two electrons, and the single hydrogen ion (H+) that is not incorporated into the NADH molecule. The other hydrogen ion (H+) is released into the surrounding medium. Thus, the reduction process essentially involves the gain of a hydride ion by the NAD+ coenzyme, turning it into NADH, which is then able to carry high-energy electrons to other locations within the cell for further biochemical processes.

User Jinesh Parekh
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