Final answer:
Scarlet fever is the disease characterized by a toxin-mediated rash and a whitish coating on the tongue. It is caused by some strains of group A streptococcus bacteria.
Step-by-step explanation:
The disease characterized by the appearance of a toxin-mediated rash and a whitish coating on the tongue is Scarlet fever. Scarlet fever is caused by some strains of group A streptococcus bacteria, which produce an erythrogenic toxin. This toxin attacks the plasma membranes of capillary endothelial cells and leads to a disseminated fine red rash on the skin, as well as a red rash on the tongue, known as strawberry tongue.