226k views
5 votes
What is the association between non-small cell lung cancer (NSCLC) and hypercalcemia?

User Yisell
by
8.8k points

1 Answer

2 votes

Final answer:

Non-small cell lung cancer (NSCLC) can be associated with hypercalcemia, which is characterized by abnormally high levels of calcium in the blood. NSCLC tumors can produce a hormone called parathyroid hormone-related protein (PTHrP), which can lead to hypercalcemia by affecting calcium regulation in the body. Hypercalcemia in NSCLC can cause various symptoms.

Step-by-step explanation:

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for about 85% of cases. Hypercalcemia, which refers to abnormally high levels of calcium in the blood, can be associated with NSCLC. In some cases, NSCLC tumors can produce a hormone called parathyroid hormone-related protein (PTHrP), which can lead to hypercalcemia by increasing the release of calcium from bones and decreasing calcium excretion from the kidneys. Hypercalcemia in NSCLC can cause symptoms such as fatigue, confusion, constipation, and loss of appetite.

User Brian Leathem
by
8.3k points