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What are the electrolyte changes in tumor lysis syndrome?

1) Hyperkalemia, hyperphosphatemia, hypocalcemia, and hyperuricemia
2) Hypokalemia, hypophosphatemia, hypercalcemia, and hyperuricemia
3) Hyperkalemia, hyperphosphatemia, hypercalcemia, and hypouricemia
4) Hypokalemia, hyperphosphatemia, hypocalcemia, and hypouricemia

1 Answer

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Final answer:

Tumor lysis syndrome can lead to changes in electrolyte levels, including hyperkalemia, hyperphosphatemia, hypocalcemia, and hyperuricemia.

Step-by-step explanation:

Tumor lysis syndrome is a condition that occurs when cancer cells break down rapidly and release their contents into the bloodstream. This can lead to significant changes in electrolyte levels in the body.

The correct answer is 1) Hyperkalemia, hyperphosphatemia, hypocalcemia, and hyperuricemia. In tumor lysis syndrome, there is an increase in potassium (hyperkalemia), an increase in phosphate (hyperphosphatemia), a decrease in calcium (hypocalcemia), and an increase in uric acid (hyperuricemia).

For example, when cancer cells break down, they release potassium into the bloodstream, which can lead to hyperkalemia. The release of phosphate can result in hyperphosphatemia. The breakdown of cancer cells also leads to the release of uric acid, which can cause hyperuricemia. Additionally, the binding of calcium by the released phosphate can result in hypocalcemia.

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