Final answer:
In treating pheochromocytoma, α-antagonists should be used first to control blood pressure, while β-antagonists can be added later to stabilize heart rate.
Step-by-step explanation:
In treating pheochromocytoma, α-antagonists should be used first.
Pheochromocytoma is a tumor of the adrenal gland that causes the release of excess catecholamines, such as epinephrine and norepinephrine. α-antagonists, also known as alpha blockers, work by blocking the alpha receptors on blood vessels, allowing them to dilate and reducing blood pressure. This helps to control the symptoms associated with pheochromocytoma, such as hypertension and palpitations.
Once blood pressure is adequately controlled with α-antagonists, β-antagonists, also known as beta blockers, can be added to further stabilize heart rate and reduce the effects of excess catecholamines on the heart.