Final answer:
Ribavirin and sofosbuvir are nucleic acid synthesis inhibitors of antiviral medication that are effective against the Hep C virus.
Step-by-step explanation:
The nucleic acid synthesis inhibitors of antiviral medication that are effective against the Hep C virus include ribavirin and sofosbuvir. Ribavirin interferes with both DNA and RNA synthesis, reducing pools of guanosine triphosphate (GTP) and inhibiting the RNA polymerase of the Hep C virus. Sofosbuvir is a uridine analog that interferes with viral polymerase activity. It is commonly coadministered with ribavirin for the treatment of hepatitis C.