Question

What is the mechanism of action of antifungal medications called Polyenes?

1) They bind to ergosterol in the cytoplasmic membrane of fungi
2) They cause fungal cells to leak
3) They inhibit the synthesis of ergosterol
4) They disrupt the cell wall of fungi

Answer 1

Polyenes in antifungal medications bind to ergosterol in the cytoplasmic membrane of fungi, disrupting the membrane integrity and causing fungal cells to leak.

Step-by-step explanation:

The mechanism of action of antifungal medications called Polyenes is that they bind to ergosterol in the cytoplasmic membrane of fungi. By binding to ergosterol, polyenes disrupt the fungal cell membrane integrity, leading to the leakage of cell contents and ultimately the death of the fungus.