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What decrease in CMRO2 is associated with burst suppression?

User Darc
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Final answer:

Burst suppression is an EEG pattern associated with a significant decrease in CMRO2, which could be more than 50%, serving as a protective mechanism for the brain during periods of stress.

Step-by-step explanation:

The question pertains to the changes in cerebral metabolic rate of oxygen consumption (CMRO2) that are associated with burst suppression on an electroencephalogram (EEG). Burst suppression is a pattern seen on EEG where there are alternating periods of high-amplitude spikes (bursts) and flat line EEG (suppression). This pattern can occur under conditions such as deep anesthesia, hypothermia, or severe brain injury. Studies have shown that when the brain enters a state of burst suppression, the CMRO2 can decrease significantly. This reduction in metabolic demand is seen as a protective mechanism against further neuronal damage during periods of limited oxygen supply or reduced cerebral blood flow.

It is important to note that the exact decrease in CMRO2 can vary depending on the individual circumstances, but reductions of 50% or more have been reported in the literature. This is crucial in medical settings, especially during surgeries that require induced coma or in the management of certain neurological conditions.

User Thybzi
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