Final answer:
Tetracycline and chloramphenicol are antibiotics that inhibit protein synthesis.
Step-by-step explanation:
The major class(es) of antibiotics that inhibit protein synthesis are:
- Tetracycline: Blocks the A site on the bacterial ribosome, preventing tRNA binding and inhibiting protein synthesis in bacteria.
- Chloramphenicol: Blocks peptidyl transfer, which affects the growth of the protein chain.