Final answer:
Magnesium has various pharmacologic mechanisms and clinical effects on Pre-E, including impacts on tyrosine kinase activity, translocation of GLUT4, the MEK-ERK cascade, and cell proliferation. Magnesium supplementation can also help with metabolic abnormalities, insulin resistance, glucose utilization, fasting circulating lipid profile, and blood pressure.
Step-by-step explanation:
Magnesium has several pharmacologic mechanisms and clinical effects in Pre-E (pre-eclampsia). It has been demonstrated to impact tyrosine kinase activity at the IR level as well as the translocation of GLUT4 to the cellular membrane. Magnesium also plays a role in the regulation of the MEK-ERK cascade and cell proliferation. Additionally, magnesium supplementation has been shown to have beneficial effects on metabolic abnormalities, insulin resistance, glucose utilization, fasting circulating lipid profile, and blood pressure.