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What are the physiological effects of mannitol? How is it dosed?

User Samanda
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Final answer:

Mannitol is an osmotic diuretic that is used to reduce brain swelling. It works by decreasing blood pressure, increasing glomerular filtration rate, and decreasing sodium reabsorption in the kidneys.

Step-by-step explanation:

Osmotic diuretics, such as mannitol, promote water loss by osmosis. Mannitol is often administered to reduce brain swelling after head injury. It acts as a vasodilator, decreasing blood pressure and increasing glomerular filtration rate, which leads to increased urine output. Additionally, mannitol decreases sodium reabsorption in the kidneys, further promoting water loss.

User Hafsa Saleem
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