Final answer:
The work of breathing is increased in COPD patients due to changes in lung compliance and resistance, making breathing more difficult.
Step-by-step explanation:
The work of breathing is increased in COPD (Chronic Obstructive Pulmonary Disease) patients due to changes in the compliance and resistance of the lungs. COPD is characterized by a breakdown of connective tissues in the lungs, reducing the number and elasticity of alveoli. As a result, air becomes trapped in the lungs, making breathing more difficult. Additionally, increased resistance in the airways further obstructs airflow, making breathing even harder.