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What are the considerations for anesthetic in carcinoid syndrome? What are the consequences of using a triggering agent?

User Samul
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Final answer:

Anesthetic considerations in carcinoid syndrome include avoiding triggering agents to prevent carcinoid crisis, and the consequences of using a triggering agent can lead to life-threatening complications such as hemodynamic instability and respiratory distress.

Step-by-step explanation:

The considerations for anesthetic in carcinoid syndrome revolve around preventing the release of vasoactive substances such as serotonin, histamine, bradykinin, and tachykinins, which the tumor can produce. These substances can lead to carcinoid crisis, which is characterized by severe hypertension, tachycardia, bronchospasm, and flushing. To mitigate these risks, avoiding triggering agents such as those that cause histamine release is crucial.

During preoperative preparation, the surgeon, nurse, and anesthesia professional should review the key concerns for the recovery and care of the patient with carcinoid syndrome. This includes the careful selection of anesthetic agents to avoid those that can trigger a carcinoid crisis. Additionally, medications such as octreotide may be administered prophylactically to inhibit the release of tumor secretagogues.

The consequences of using a triggering agent during anesthesia can lead to the life-threatening complication of carcinoid crisis. This may result in hemodynamic instability and respiratory distress, which can significantly complicate the anesthetic management and potentially necessitate intensive care postoperatively. Understanding the pathophysiology of carcinoid syndrome and the strict avoidance of triggering agents is essential in delivering safe anesthetic care to these patients.

User Andrey Sidorov
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