Final answer:
COX-2 inhibitors have various side effects including increased cancer risk, heart problems, and gastrointestinal issues. They may also cause insomnia, increased heart rate, and hypertension. NSAIDs like aspirin also have their own set of side effects.
Step-by-step explanation:
COX-2 inhibitors, such as Celebrex, have side effects that include increased risk of colon cancer, osteoporosis, heart disease, macular degeneration, and possibly depression. They can also cause insomnia, prostate enlargement, increased heart rate, hypertension, and an increased probability of heart attacks. Other common side effects include indigestion, heartburn, stomach pain, nausea, diarrhea, constipation, and weight gain or loss.
Nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, also have side effects such as an increased risk of gastrointestinal ulcers and bleeds, heart attack, and kidney disease.