Question

What are the types of Heparin induced thrombocytopenia?

1) Type 1
2) Type 2
3) Clinical diagnosis

Answer 1

Heparin induced thrombocytopenia (HIT) has two types: Type 1 and Type 2. Type 1 is non-immune-mediated and mild, while Type 2 is immune-mediated, severe, and can lead to thrombosis. Clinical diagnosis can also be used in some cases.

Step-by-step explanation:

The types of Heparin induced thrombocytopenia (HIT) are:

1. Type 1: This type is non-immune-mediated and occurs within the first 2 days of heparin exposure. It is usually mild and transient, with the platelet count returning to normal without any clinical symptoms.
2. Type 2: This type is immune-mediated and occurs after 5-14 days of heparin exposure. It is more severe and can lead to thrombosis. Type 2 HIT is caused by the formation of antibodies against heparin-platelet factor 4 (PF4) complexes.
3. Clinical diagnosis: In some cases, HIT may be diagnosed clinically based on a drop in platelet count without laboratory confirmation.