Question

What is the effect of inhalational anesthetics at greater than 1 MAC on CBF/CMRO2?

1) Increase CBF and CMRO2
2) Decrease CBF and CMRO2
3) Increase CBF and decrease CMRO2
4) Decrease CBF and increase CMRO2

Answer 1

Inhalational anesthetics at greater than 1 MAC decrease CBF (Cerebral Blood Flow) and CMRO2 (Cerebral Metabolic Rate of Oxygen).

Step-by-step explanation:

Inhalational anesthetics at greater than 1 MAC have the effect of decreasing CBF (Cerebral Blood Flow) and decreasing CMRO2 (Cerebral Metabolic Rate of Oxygen)

When inhalational anesthetics are administered at concentrations higher than 1 MAC, they act as potent cerebral vasodilators, causing a decrease in CBF. Additionally, these anesthetics suppress the neuronal activity, leading to a decrease in CMRO2 as well. Therefore, the correct answer is option 2) Decrease CBF and CMRO2.