Final answer:
Contraindications of calcium channel blockers, such as diltiazem and verapamil, include heart block, low blood pressure, severe heart failure, and liver or kidney problems.
Step-by-step explanation:
Contraindications are factors or conditions that make it unsafe or inappropriate to use a certain medication. For calcium channel blockers, such as diltiazem and verapamil, some contraindications include:
- Heart block: Calcium channel blockers can further slow down the heart rate, which can be dangerous in people with heart block.
- Low blood pressure: These medications can lower blood pressure, so they may not be suitable for people with already low blood pressure.
- Severe heart failure: Calcium channel blockers can worsen heart failure symptoms and should be used with caution in these patients.
- Liver or kidney problems: Diltiazem and verapamil are metabolized by the liver and excreted by the kidneys, so they may not be recommended for people with severe liver or kidney dysfunction.