Final answer:
Amphotericin B is an anti-fungal drug that can be used to treat serious systemic fungal infections such as aspergillosis, cryptococcal meningitis, histoplasmosis, blastomycosis, and candidiasis. However, it does come with some serious side effects that need to be considered.
Step-by-step explanation:
The anti-fungal drug that can be used to treat serious systemic fungal infections is Amphotericin B. It is commonly used for infections such as aspergillosis, cryptococcal meningitis, histoplasmosis, blastomycosis, and candidiasis. While it was the only antifungal drug available for several decades, it does come with some serious side effects. It is important to balance the risks and benefits of using this medication.