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What is the major complication of prolonged intubation for more than 48 hours?

1) Ventilator-associated pneumonia
2) Tracheal stenosis
3) Ventilator-associated lung injury
4) Ventilator-associated diaphragm dysfunction

User Sabria
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Final answer:

The major complication of prolonged intubation for more than 48 hours is ventilator-associated pneumonia (VAP).

Step-by-step explanation:

The major complication of prolonged intubation for more than 48 hours is ventilator-associated pneumonia (VAP). When a breathing tube is inserted into the trachea, it bypasses the body's natural defense mechanisms and allows bacteria to enter the lungs, leading to pneumonia. VAP can be prevented by implementing proper infection control measures such as regular oral care, hand hygiene, and removing the breathing tube as soon as it is no longer needed.

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