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How is delivery of Na⁺ to distal nephron related to serum aldosterone under normal circumstances?

User Bershika
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Final answer:

Aldosterone stimulates the synthesis and activation of the sodium-potassium pump, which causes an increase in blood sodium levels and blood volume.

Step-by-step explanation:

In the distal convoluted tubules and collecting ducts of the kidneys, aldosterone stimulates the synthesis and activation of the sodium-potassium pump. Sodium passes from the filtrate, into and through the cells of the tubules and ducts, into the ECF and then into capillaries. Water follows the sodium due to osmosis. Thus, aldosterone causes an increase in blood sodium levels and blood volume. Aldosterone's effect on potassium is the reverse of that of sodium; under its influence, excess potassium is pumped into the renal filtrate for excretion from the body.

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