Final answer:
Mid epigastric pain that worsens when eating is most likely due to a peptic ulcer, a common condition caused by an infection and characterized by irritation from acidic gastric juice.
Step-by-step explanation:
The cause of mid epigastric pain that worsens when eating could be due to several conditions, among which peptic ulcer disease is a highly probable cause. A peptic ulcer is a sore in the lining of the stomach or duodenum which is often caused by an infection with the bacterium Helicobacter pylori. The pain associated with a gastric ulcer is partly due to irritation of the ulcerated tissue by acidic gastric juice. The typical pain from a peptic ulcer generally occurs at night and tends to improve with eating, although this is not always the case. Other potential causes for such pain can include gastritis, gallstones, or pancreatitis, necessitating medical evaluation to determine the exact diagnosis and appropriate treatment.