Final answer:
Dependence refers to when an individual believes they need a certain drug to function. It can be physical or psychological, and is different from tolerance and addiction.
Step-by-step explanation:
The correct answer is 2) Dependence. When an individual feels that they need a certain drug to function, it indicates that they have developed dependence on the drug. Dependence can be physical or psychological. Physical dependence involves changes in normal bodily functions and leads to withdrawal symptoms when drug use is stopped. Psychological dependence, on the other hand, is an emotional need for the drug. Tolerance, on the other hand, refers to the need for higher doses of the drug to achieve the same effects, while addiction is the compulsive use of a drug despite negative consequences.