Final answer:
Too little secretion of cortisol is known to cause Addison's disease, a form of adrenal insufficiency characterized by symptoms such as fatigue, low blood pressure, and hyperpigmentation.
Step-by-step explanation:
Too little secretion of cortisol causes Addison disease. This condition, also known as adrenal insufficiency, is reflected by a range of symptoms such as low blood pressure, fatigue, and cravings for salty foods. It arises either from direct adrenal gland dysfunction or from insufficient ACTH secretion by the pituitary gland, which can be due to a pituitary tumor. People with Addison's disease often experience symptoms like hyperpigmentation of the skin, hypoglycemia (low blood sugar), and low blood sodium levels. The treatment usually involves lifelong cortisol replacement therapy.