Final answer:
The letter 'E' in the ABCDE acronym for primary assessment in medicine stands for 'Exposure', which entails fully examining a patient by removing clothing and considering environmental elements.
Step-by-step explanation:
The E in the ABCDE primary assessment acronym stands for Exposure. This comes after Airway, Breathing, Circulation, and Disability in the assessment sequence. In a medical context, especially during trauma assessments, Exposure refers to removing the patient's clothing to allow for a full evaluation of injuries or underlying conditions without missing anything that could be hidden by clothing. It also pertains to assessing the environmental factors that may contribute to the patient's condition, such as extreme temperatures.